Cancer Etiology, Evolution, Early Detection and Risk Prediction
Mathematical Modeling – Biostatistics

Associate Professor

Division of Biostatistics and Bioinformatics, Department of Oncology

Johns Hopkins Medicine, Sidney Kimmel Comprehensive Cancer Center

Sidney Kimmel Comprehensive Cancer Center
Johns Hopkins University School of Medicine
550 North Broadway, Suite 1103
Baltimore, MD 21205 USA

Department of Biostatistics

Johns Hopkins Bloomberg School of Public Health

Johns Hopkins Bloomberg School of Public Health
615 North Wolfe Street, Office E3533
Baltimore, MD 21205 USA


1/2011 - 6/2013

Postdoc, Biostatistics

Harvard University & Dana-Farber Cancer Institute


Ph. D., Applied Mathematics

University of Maryland, College Park

Bad Luck Theory

Cristian Tomasetti and Bert Vogelstein explain their Bad Luck Theory

Two factors are widely recognized as causing cancer: environment (E) and heredity (H).

A paper published in Science in 2015 provided evidence for a third factor: the random mistakes made when normal stem cells divide. The results in this paper showed that there was a strong correlation between the lifetime number of normal stem cell divisions in an organ and its lifetime cancer incidence. This contributes to explain why certain cancer types have a much higher incidence than others....